John Q. Wang is a Westport Anesthesia/Missouri Endowed Chair in the Department of Anesthesiology and a Professor in the Departments of Anesthesiology and Basic Medical Science at UMKC School of Medicine since 2004. He earned his medical degree in Tongji Medical University in 1982 and his Ph.D. in Shanghai Medical University in 1988. Dr. Wang’s research primarily focuses on drug abuse and addiction. He currently leads a research team supported by NIH grants to conduct animal experiments from molecule to behavior and from in vitro to in vivo. In addition, Dr. Wang is interested in elucidating molecular mechanisms for anesthesia induction.
Mao LM, Fibuch EE and Wang JQ. (2010). Decoding BDNF-LTP coupling in cocaine addiction. Neuron. 67: 679-681.
Guo ML, Fibuch EE, Liu XY, Choe ES, Buch S, Mao LM and Wang JQ. (2010). CaMKIIα interacts with M4 muscarinic receptors to control receptor and psychomotor function. EMBO J. 29: 2070-2081.
Yao H, Yang Y, Kim KJ, Bethel-Brown C, Gong N, Funa K, Gendelman HE, Su TP, Wang JQ and Buch S. (2010). Molecular mechanisms involving sigma receptor-mediated induction of MCP-1: implication for increased monocyte transmigration. Blood. 115: 4951-4962.
Mao LM, Wang W, Chu XP, Zhang GC, Liu XY, Yang YJ, Haines M, Papasian CJ. Fibuch EE, Buch S, Chen JG, Wang JQ. (2009). Stability of surface NMDA receptors controls synaptic and behavioral adaptations to amphetamine. Nat Neurosci. 12:602-610. PMC2749993.
Liu XY, Mao LM, Zhang GC, Papasian CJ, Fibuch EE, Lan HX, Zhou HF, Xu M and Wang JQ. (2009). Activity-dependent modulation of limbic dopamine D3 receptors by CaMKII. Neuron. 61:425-438. PMC2650276.
Liu XY, Chu XP, Mao LM, Wang M, Lan HX, Li MH, Zhang GC, Parelkar NK, Fibuch EE, Haines M, Neve KA, Liu F, Xiong ZG and Wang JQ. (2006). Modulation of D2R-NR2B interactions in response to cocaine. Neuron. 52:897-909.
Yang L, Mao L, Chen H, Catavsan M, Kozinn J, Arora A, Liu X and Wang JQ. (2006). A signaling mechanism from Gαq-protein-coupled glutamate receptors to gene expression: role of the c-Jun N-terminal kinase pathway. J Neurosci. 26: 971-980.
Mao L, Yang L, Tang Q, Samdani S, Zhang G and Wang JQ. (2005). The scaffold protein Homer1b/c links metabotropic glutamate receptor 5 to extracellular signal-regulated protein kinase cascades in neurons. J Neurosci. 25: 2741-2752.
Yang L, Mao L, Tang Q, Samdani S, Liu Z and Wang JQ. (2004). A novel Ca2+-independent signaling pathway to extracellular signal-regulated protein kinase by coactivation of NMDA receptors and metabotropic glutamate receptor 5 in neurons. J Neurosci. 24: 10846-10857.