Pathology

Faculty & Staff


Photo of Kamani Lankachandra, M.D.
Kamani Lankachandra, M.D.
Professor, UMKC School of Medicine Truman Medical Center Hospital HillPathology
  • Department Chair
Photo of Alexey Glazyrin, M.D., Ph.D.
Alexey Glazyrin, M.D., Ph.D.
Assistant Professor, UMKC School of Medicine Truman Medical Center Hospital HillPathology
  • Program Director
  • Hematopathology Director
Photo of Gail Murray, MBA
Gail Murray, MBA
Truman Medical Center Hospital HillPathology Administration
  • Residency Program Coordinator
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Photo of Daniel Dim, M.D.
Daniel Dim, M.D.
Associate Professor, UMKC School of Medicine Truman Medical Center Hospital HillPathology
  • Anatomic Pathology Director
Cynthia Essmyer, M.D.
Clinical Assistant Professor of Medicine, UMKC School of Medicine Saint Luke’s Hospital
  • Director, Microbiology Laboratory
Photo of Hana Hamdan, M.D.
Hana Hamdan, M.D.
Assistant Professor, UMKC School of Medicine Truman Medical Center Hospital HillPathology
  • Director, Transfusion Services
Photo of Soheila Hamidpour, M.D.
Soheila Hamidpour, M.D.
Assistant Professor, UMKC School of Medicine Truman Medical Center Hospital HillPathology
  • Director of Clinical Chemistry
Photo of Michael Handler, M.D., MMM
Michael Handler, M.D., MMM
Associate Clinical Professor, UMKC School of Medicine PathologyMedical Director for the Missouri Center for Patient Safety

Vice President Medical Affairs/Chief Medical Officer
SSM St. Joseph Hospital West

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Michael Handler, MD, MMM is the Medical Director for the Missouri Center for Patient Safety and the Vice President of Medical Affairs/Chief Medical Officer for SSM St. Joseph Hospital West in Lake Saint Louis, Missouri.

As VPMA/chief medical officer since 2007, Dr. Handler serves as liaison between the organized medical staff and administration, which advances the clinical practice of medicine for the campus.  Dr. Handler has been a physician in Missouri since 1985.  He operated a private Obstetrics and Gynecology practice in suburban St. Louis from 1989 through 2007 and has served as a house obstetric physician for SSM St. Joseph Hospital West from 2007 through present.  Dr. Handler has an avid passion for patient safety and quality and has implemented many successful quality improvement initiatives.  He serves as the network physician champion for TeamSTEPPS for the six hospitals in SSM St. Louis.

Dr. Handler earned his medical degree at University of Missouri-Kansas City School of Medicine in 1984.  He completed his residency in obstetrics and gynecology at St. Louis University Hospitals in 1989 and earned his Master of Medical Management from Tulane University in 2008.

Photo of Carole McArthur, M.D., Ph.D.
Carole McArthur, M.D., Ph.D.
Clinical Professor, UMKC School of Medicine Truman Medical Center Hospital HillPathology
  • Research Co-Director
Photo of Agostino Molteni, M.D., Ph.D., F.A.C.C.B.
Agostino Molteni, M.D., Ph.D., F.A.C.C.B.
Director of Student Research UMKC School of Medicine
  • Professor of Pathology & Pharmacology – UMKC School of Medicine
  • Professor Emeritus of Pathology – Northwestern University
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Research Interests

Dr. Molteni’s main research interest is the study of development of interstitial pulmonary fibrosis (IPF) in several models of experimental lung injury: exposure to radiation and hypoxia, administration of bleomycin and fat embolism syndrome. Also studied is the role played by the renin angiotensin system in the development of fibrosis and the antifibrotic protection of angiotensin converting inhibitors or angiotensin II receptor blockers.

His projects are conducted in cooperation with Dr. Betty Herndon (UMKC SOM); Dr. T. McIff, Dept. of Orthopedic Surgery and Dr. A. Poisner, Dept. of Pharmacology, University of Kansas Medical Center, Dr. B. Uhal, Dept. of Physiology, Michigan State University, Dr. R. Baybutt, Dept. of Health Sciences, Wheaton College, Wheaton, IL., Dr. G Van Den Heuvel, Dept. of Physiology, Eastern Michigan University, Kalamazoo, MI.

Research Career Development Award, National Institutes of Health, 1972
Albert E. Lasker Award, 1980, to NHLBI sharing as principal investigator, Central Laboratory Hypertension Detection and Follow-up Program
Meritorious Service Award, Chicago Heart Association,1982
Clinical Chemists Recognition Award, 1983

Recent research includes the evaluation of exenatide in a rodent model of non-alcoholic liver steatosis, and in particular, the drug’s effect on the pancreas and the thyroid of these animals. This study was performed in cooperation with Dr. Herndon, Dr. Laura Alba, and others of the Dept. of Medicine, in the UMKC SOM. An additional study is the evaluation of pulmonary and cardiac damage in a model of Cux-1 mice expressing the cyclin kinase inhibitors P21 and P27 (Drs Baybutt and Van Den Heuvel).

Selected Publications

Has published more than 200 articles and book chapters and more than 370 presentations at national and international scientific meetings.

Curcumin Effects on Hepatic Steatosis and Histopathology in an Obese Mouse Model. British Journal of Medicine and Medical Research: 5(8): 1017-1023, 2015. Article no BJMMP.2015.112

Fat Embolism sensitizes rats to a “second hit” with LPS: an animal model of Pulmonary Fibrosis: Journal of Trauma and Acute Surgical Care; 783:552-557, 2015

Fat Embolism Syndrome following caesarean section in an obese patient and it’s similarity to an animal model of the same syndrome: a case report. Case reports in Clinical Pathology: Published online 3-3-2015, D01110.5430/crcp.vnp

NF-KB controls Resistance of Human Salivary Gland (HSG) Cells to apoptosis in an in vitro model of Sjögren syndrome. Open Journal of Rheumatology and Auto immune Diseases (OJRA): Vol 4 #3; ID: 2040 128, 2014

Mitigating effect of Captopril and Losartan on Lung Histopathology in a rat model of Fat Embolism. The Journal of Trauma 70 (5):1186-1191; 2011

Biochemical and Histological Effects of Exendin 4 (exenatide) in the rat pancreas. Diabetologia53(1):153-159; 2010

“Persistent and progressive fibrotic changes in a model of fat embolism.” Journal of Trauma 72 (h) 992-998, 2012

“Dietary flaxseed oil protects against bleomycin-induced pulmonary fibrosis in rats.” Pulmonary Medicine, published on line, June 2012 10457031 doi 0.1155/2012/457031

“Urease and Helicobacter spp. Antigens in Pulmonary Granuloma” Journal of Comparative Pathology(2012) http://dx.doi.org/10.1016/j.jcpa.2012.06.011

“Effect of exendin (exenatide) on the thyroid and parathyroid gland in a rat model.” Eur. J., of Pharmacology 2012 http://dx.doi.org/10.1016/j.ejphar.2012.07.024 

Cathi Murphey Half, Ph.D, HCLD/CC (ABB)
Midwest Transplant Network Director Histocompatibility and Immunogenetics LaboratoryPathology
Photo of Evanthia Omoscharka, M.D.
Evanthia Omoscharka, M.D.
Assistant Professor, UMKC School of Medicine Truman Medical Center Hospital HillPathology
  • Director, Point of Care
Photo of Christopher Papasian, Ph.D. (ABMM)
Christopher Papasian, Ph.D. (ABMM)
Work M3-CO3 Work Phone: (816) 235-5172

Professor & Chairman, Basic Medical Science, UMKC School of Medicine
Microbiology Consultant, Truman Medical Center

  • Microbiology; SUNY Buffalo – Ph.D. (1982)
  • Veterinary Science; University of Idaho – M.S. (1978)
  • Forest Zoology; SUNY College of Environmental Science & Forestry – B.S. (Magna cum laude: 1976)
  • Zoology; Syracuse University – B.S. (Magna cum laude: 1976)
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Biography

Chris Papasian is Board Certified in Medical and Public Health Microbiology. He was trained as a classical immunology researcher in both cellular and humoral immunity, then opted to pursue postdoctoral training in Medical and Public Health Microbiology. He served as Director of Diagnostic Microbiology and Immunology Laboratories at major teaching hospitals from 1984-1998. He currently serves as a Microbiology Consultant for Truman Medical Center, a primary teaching hospital for the UMKC School of Medicine.

Dr. Papasian is course director for the Medical Microbiology Course offered to medical students at UMKC.

Research Interest

Dr. Papasian does not currently maintain his own active research laboratory but contributes to the research of several faculty within the department. His primary personal research interest lies in the area of the host response to serious infections.

Editor

Clinical and Vaccine Immunology, 7/2012-Present

Editorial Boards

Journal of Clinical Microbiology, 1/1996 – 12/2004; 1/2006 – Present

Clinical and Vaccine Immunology, 1/2005 – 7/2012

 

Recent Publications

Qureshi, AA, Guan, XQ, Reis, JC, Papasian, CJ, Jabre, S, Morrison, DC, Qureshi, N. 2012. Inhibition of nitric oxide and inflammatory cytokines in LPS-stimulated murine macrophages by resveratrol, a potent proteasome inhibitor. Lipids in Health and Disease. 11:76

Fu, M., Miao, R., Huang, S., Zhou, Z., Quinn, T., Van Treek, B., Nayyar, T., Dim, D., Jiang, Z., Papasian, C., Y Chen, Y., and Liu, G. 2013. Targeted Disruption of MCPIP1/Zc3h12a Results in Fatal Inflammatory Disease. Immunol. Cell Biol. doi:10.1038/icb.2013.11

Qureshi, A.A., Khan, D.A., Mahjabeen, W., Papasian, C.J. and Qureshi, N. 2013. Nutritional Supplement-5 with a Combination of Proteasome Inhibitors (Resveratrol, Quercetin, δ-Tocotrienol) Modulate Age-Associated Biomarkers and Cardiovascular Lipid Parameters in Human Subjects. J. Clin. Experimental Cardiology. 4:238.

Zhou Z, Miao R, Huang S, Elder B, Quinn T, Papasian CJ, Zhang J, Fan D, Chen YE, Fu M. 2013. MCPIP1 Deficiency in Mice Results in Severe Anemia Related to Autoimmune Mechanisms. PLoS One. 2013 Dec 6;8(12):e82542. doi: 10.1371/journal.pone.0082542

Pei YF, Zhang L, Liu Y, Li J, Shen H, Liu YZ, Tian Q, He H, Wu S, Ran S, Han Y, Hai R, Lin Y, Zhu J, Zhu XZ, Papasian CJ, Deng HW. 2014. Meta-analysis of genome-wide association data identifies novel susceptibility loci for obesity. Hum Mol Genet. 23(3):820-30. doi: 10.1093/hmg/ddt464

Huang HL, Lv C, Zhao YC, Li W, He XM, Li P, Sha, AG, Xiao Tian X, Papasian CJ, Deng HW, Lu GX, Xiao HM. 2014. Mutant ZP1 in Familial Infertility. NEJM In Press

Fred Plapp, M.D., Ph.D.
Saint Luke’s Hospital
Photo of Diane Peterson, M.D.
Diane Peterson, M.D.
Clinical Assistant Professor, UMKC School of Medicine Jackson County Medical ExaminerPathology
  • Chief Medical Examiner – JCME