The UMKC Shock Trauma Research Center is engaged in research to develop new treatment strategies to reduce the amount of cell death that occurs following shock. Besides studies in shock, the research programs of the Center include basic studies to understand the molecular events that allow cells of the immune system to “recognize” the presence of microbes and microbial products, and to communicate that information to white blood cells
Dr. Van Way’s activities have centered around hemorrhagic shock, and to exploring the basic mechanisms of cell injury during hemorrhagic shock and resuscitation, and to identify changes which produce long-term damage. In the past several years, his research team has carried out basic and clinical studies of the genomic response to shock and injury, and has developed several potential therapeutic agents for the treatment of hemorrhagic shock. Currently, his team is exploring the mechanisms by which cells adjust to the low-oxygen environments which characterize low perfusion states such as septic and hemorrhagic shock.