A report by School of Medicine faculty on tPA (tissue plasminogen activator) as a treatment for abscesses following perforated appendicitis received the “Best Paper Award” at the combined British Association of Pediatric Surgeons (BAPS) and International Pediatric Endosurgery Group (IPED) meeting July 22-26 in Edinburgh, Great Britain.
Shawn St. Peter, M.D., professor of surgery and Director of the Children’s Mercy Hospital Center for Prospective Clinical Trials, coordinated the study and presented the paper. Doug C. Rivard, D.O., associate professor and chair of radiology at CMH, was a senior author.
The paper evaluated the effectiveness of tPA in resolving abscesses that developed following perforated appendicitis. The study found no advantage to using tPA over saline for irrigation of the abscess cavity, and that there was actually increased drainage and additional cost with use of the tPA.
Other authors included Sohail Shah, M.D., assistant professor of surgery, David Juang, M.D., assistant professor of surgery, Brent Reading, M.D., assistant professor of radiology, Brent Culley, George W. Holcomb III, M.D./MBA, professor of surgery, and Susan Sharp, Ph.D., the study’s clinical coordinator.
The meeting was the first joint meeting of the BAPS and IPEG and drew more than 700 pediatric surgeons from around the world.