School of Medicine researcher published in New England Journal of Medicine

 Daniel Pauley, M.D., PH.D.
Daniel Pauley, M.D., Ph.D.

Daniel F. Pauly, M.D., Ph.D., professor of medicine, biomedical and health informatics, and chief of cardiology, is co-author of a research article published in the Jan. 21 issue of the New England Journal of Medicine.

The article examined peripartum cardiomyopathy — deterioration of heart function for women in their last month of pregnancy and up to six months postpartum — and how it shares some clinical features with idiopathic dilated cardiomyopathy, a disorder caused by mutations in more than 40 genes, including TTN, which encodes a protein.

“Peripartum cardiomyopathy is a poorly understood, life-threatening disorder,” Pauly said. “Our hope is that unraveling its molecular causes will lead to more effective treatments for the young mothers it afflicts.”

Pauly started at the School of Medicine in 2013.

The New England Journal of Medicine, first published in 1812, is the most widely read, cited and influential general medical periodical in the world.